metabolic disease

metabolic

[met″ah-bol´ik] pertaining to or of the nature of metabolism.metabolic disease a disease caused by some defect in the chemical reactions of the cells of the body.metabolic syndrome a combination including at least three of the following: abdominal obesity, hypertriglyceridemia, low level of high-density lipoproteins, hypertension, and high fasting plasma glucose level. It is associated with an increased risk for development of diabetes mellitus" >diabetes mellitus and cardiovascular disease.

met·a·bol·ic dis·ease

generic term for disease caused by an abnormal metabolic process. It can be congenital, due to inherited enzyme abnormality, or acquired, due to disease of an endocrine organ or failure of function of a metabolic important organ such as the liver.

paraneoplastic syndrome

Oncology A co-morbid condition due to the indirect–remote or 'biologic' effects of malignancy, which may be the first sign of a neoplasm or its recurrence; PSs occur in > 15% of CAs, are caused by hormones, growth factors, biological response modifiers, and other as-yet unidentified factors, and may regress with treatment of the primary tumor. See Ectopic hormone. Paraneoplastic syndromes GI tract, eg anorexia, vomiting, protein-losing enteropathy, liver disease Hematologic, eg leukemoid reaction, reactive eosinophilia, peripheral 'cytoses or 'cytopenias, hemolysis, DIC, thromboembolism, thrombophlebitis migrans Hormonal effects Metabolic disease, eg lactic acidosis, hypertrophic pulmonary osteoarthropathy, hyperamylasemia, hyperlipidemia Neuromuscular, eg peripheral neuropathy, myopathy, CNS, spinal cord degeneration, inflammation Renal, eg nephrotic syndrome, uric acid nephropathy Skin, eg bullous mucocutaneous lesions, acquired ichthyosis, acanthosis nigricans, dermatomyositis Others, eg callus formation, hypertension, and amyloidosis

acute abdomen

A relatively nonspecific symptom complex, in which a Pt is first seen in a 'toxic' state, complaining of incapacitating abdominal pain, variably accompanied by fever, and leukocytosis; AA may also be defined as an acute intra-abdominal inflammatory process that may require surgical intervention; appendicitis is the most common cause of an AA; nearly 100 other conditions may present in a similar fashion, in particular, ruptured ectopic pregnancy in a fallopian tube, ruptured acute diverticulitis and acute mesenteric lymphadenitis.

Acute abdomen etiology

Infection: Amebiasis, hepatitis, falciparum malaria, pneumococcal pneumonia, rheumatic fever, salmonella gastroenteritis, staphylococcal toxemia, syphilis in 'tabetic crisis,' trichinosis, TB, typhoid fever, viral enteritides, herpes zoster, infectious mononucleosis, Whipple's disease
Inflammation: Appendicitis, cholangitis, cholecystitis, Crohn's disease, diverticulitis, gastroenteritis, hepatitis, SLE, mesenteric lymphadenitis, pancreatitis, peritonitis due to organ perforation, perinephric abscesses, pyelonephritis, ulcerative colitis, intestinal obstruction, rheumatoid arthritis, polyarteritis nodosa, Henoch-Schönlein disease
Intoxication: Black widow spider bite, heavy metals, mushrooms
Ischemia: Renal infarction, mesenteric arterial thrombosis
Malignancy: Pain due to organ infarction, Hodgkin's disease ('classically' associated with alcohol ingestion), leukemia, lymphoproliferative disorders
Metabolic disease: Adrenal insufficiency (Addisonian crisis), DKA, familial hyperlipoproteinemia, familial Mediterranean fever, hemochromatosis, hereditary angioneurotic edema, hyperparathyroidism, hyperthyroidism, acute intermittent porphyria, uremia, substance abuse withdrawal
Ob/Gyn: Twisted ovarian cyst, ectopic pregnancy, endometriosis, PD
Referred pain: Pneumonia, MI, pleuritis, pericarditis, myocarditis, hematomata of the rectal muscle, renal colic, peptic ulcer, nerve root compression
Trauma: Perforation/rupture–aortic aneurysm, spleen, bladder

met·a·bol·ic dis·ease

(met-ă-bolik di-zēz) Generic term for disease caused by an abnormal metabolic process; can be congenital, due to inherited enzyme abnormality, or acquired, due to disease of an endocrine organ or failure of function of a metabolic important organ.

单词	metabolic disease
释义	metabolic disease metabolic [met″ah-bol´ik] pertaining to or of the nature of metabolism.metabolic disease a disease caused by some defect in the chemical reactions of the cells of the body.metabolic syndrome a combination including at least three of the following: abdominal obesity, hypertriglyceridemia, low level of high-density lipoproteins, hypertension, and high fasting plasma glucose level. It is associated with an increased risk for development of diabetes mellitus" >diabetes mellitus and cardiovascular disease. met·a·bol·ic dis·ease generic term for disease caused by an abnormal metabolic process. It can be congenital, due to inherited enzyme abnormality, or acquired, due to disease of an endocrine organ or failure of function of a metabolic important organ such as the liver. paraneoplastic syndrome Oncology A co-morbid condition due to the indirect–remote or 'biologic' effects of malignancy, which may be the first sign of a neoplasm or its recurrence; PSs occur in > 15% of CAs, are caused by hormones, growth factors, biological response modifiers, and other as-yet unidentified factors, and may regress with treatment of the primary tumor. See Ectopic hormone. Paraneoplastic syndromes GI tract, eg anorexia, vomiting, protein-losing enteropathy, liver disease Hematologic, eg leukemoid reaction, reactive eosinophilia, peripheral 'cytoses or 'cytopenias, hemolysis, DIC, thromboembolism, thrombophlebitis migrans Hormonal effects Metabolic disease, eg lactic acidosis, hypertrophic pulmonary osteoarthropathy, hyperamylasemia, hyperlipidemia Neuromuscular, eg peripheral neuropathy, myopathy, CNS, spinal cord degeneration, inflammation Renal, eg nephrotic syndrome, uric acid nephropathy Skin, eg bullous mucocutaneous lesions, acquired ichthyosis, acanthosis nigricans, dermatomyositis Others, eg callus formation, hypertension, and amyloidosis acute abdomen A relatively nonspecific symptom complex, in which a Pt is first seen in a 'toxic' state, complaining of incapacitating abdominal pain, variably accompanied by fever, and leukocytosis; AA may also be defined as an acute intra-abdominal inflammatory process that may require surgical intervention; appendicitis is the most common cause of an AA; nearly 100 other conditions may present in a similar fashion, in particular, ruptured ectopic pregnancy in a fallopian tube, ruptured acute diverticulitis and acute mesenteric lymphadenitis. Acute abdomen etiology Infection Amebiasis, hepatitis, falciparum malaria, pneumococcal pneumonia, rheumatic fever, salmonella gastroenteritis, staphylococcal toxemia, syphilis in 'tabetic crisis,' trichinosis, TB, typhoid fever, viral enteritides, herpes zoster, infectious mononucleosis, Whipple's disease Inflammation Appendicitis, cholangitis, cholecystitis, Crohn's disease, diverticulitis, gastroenteritis, hepatitis, SLE, mesenteric lymphadenitis, pancreatitis, peritonitis due to organ perforation, perinephric abscesses, pyelonephritis, ulcerative colitis, intestinal obstruction, rheumatoid arthritis, polyarteritis nodosa, Henoch-Schönlein disease Intoxication Black widow spider bite, heavy metals, mushrooms Ischemia Renal infarction, mesenteric arterial thrombosis Malignancy Pain due to organ infarction, Hodgkin's disease ('classically' associated with alcohol ingestion), leukemia, lymphoproliferative disorders Metabolic disease Adrenal insufficiency (Addisonian crisis), DKA, familial hyperlipoproteinemia, familial Mediterranean fever, hemochromatosis, hereditary angioneurotic edema, hyperparathyroidism, hyperthyroidism, acute intermittent porphyria, uremia, substance abuse withdrawal Ob/Gyn Twisted ovarian cyst, ectopic pregnancy, endometriosis, PD Referred pain Pneumonia, MI, pleuritis, pericarditis, myocarditis, hematomata of the rectal muscle, renal colic, peptic ulcer, nerve root compression Trauma Perforation/rupture–aortic aneurysm, spleen, bladder met·a·bol·ic dis·ease (met-ă-bolik di-zēz) Generic term for disease caused by an abnormal metabolic process; can be congenital, due to inherited enzyme abnormality, or acquired, due to disease of an endocrine organ or failure of function of a metabolic important organ.
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