a stone, usually renal, caused by a metabolic abnormality resulting in increased excretion of a substance of low solubility in urine, such as urate or cystine.
met·a·bol·ic cal·cu·lus
(metă-bolik kalkyū-lŭs) Stone, usually renal, caused by metabolic abnormality resulting in increased excretion of a substance of low solubility in urine.