Lineweaver-Burk equation

[¦līn‚wēv·ər ′bərk i‚kwā·zhən] (biochemistry) A double reciprocal form of the Michaelis-Menten equation, written as 1/ V₀= K_m/ V_max[S ] + 1/ V_max, that yields a straight-line plot for reactions obeying basic Michaelis-Menten kinetics. It provides a more accurate estimate of V_maxand is helpful in analyzing enzyme inhibition.

Lineweaver-Burk equation

Line·weav·er-Burk e·qua·tion

(līn'wē-vĕr bŭrk), a rearrangement of the Michaelis-Menten equation, 1/v = 1/V_max + (K_m/V_max)(1/[S]), where v is the velocity of the reaction, V_max is the maximum velocity, K_m is the Michaelis constant; and [S] is the substrate concentration. Compare: double-reciprocal plot. [Hans Lineweaver, Dean Burk]

Burk,

Dean, U.S. scientist, 1904–. Lineweaver-Burk equation - see under LineweaverLineweaver-Burk plot - see under Lineweaver

Lineweaver,

Hans, U.S. physical chemist, 1907–. Lineweaver-Burk equation - rearrangement of the Michaelis-Menten equation.Lineweaver-Burk plot - graphical representation of enzyme kinetic data. Synonym(s): double-reciprocal plot; Woolf-Lineweaver-Burk plot

单词	lineweaver-burk equation
释义	Lineweaver-Burk equation Lineweaver-Burk equation [¦līn‚wēv·ər ′bərk i‚kwā·zhən] (biochemistry) A double reciprocal form of the Michaelis-Menten equation, written as 1/ V₀= K_m/ V_max[S ] + 1/ V_max, that yields a straight-line plot for reactions obeying basic Michaelis-Menten kinetics. It provides a more accurate estimate of V_maxand is helpful in analyzing enzyme inhibition. Lineweaver-Burk equation Line·weav·er-Burk e·qua·tion (līn'wē-vĕr bŭrk), a rearrangement of the Michaelis-Menten equation, 1/v = 1/V_max + (K_m/V_max)(1/[S]), where v is the velocity of the reaction, V_max is the maximum velocity, K_m is the Michaelis constant; and [S] is the substrate concentration. Compare: double-reciprocal plot. [Hans Lineweaver, Dean Burk] Burk, Dean, U.S. scientist, 1904–. Lineweaver-Burk equation - see under LineweaverLineweaver-Burk plot - see under Lineweaver Lineweaver, Hans, U.S. physical chemist, 1907–. Lineweaver-Burk equation - rearrangement of the Michaelis-Menten equation.Lineweaver-Burk plot - graphical representation of enzyme kinetic data. Synonym(s): double-reciprocal plot; Woolf-Lineweaver-Burk plot
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