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lysyl oxidase
lysyl oxidase[′lī·səl ′äk·sə‚dās] (biochemistry) Any of a group of enzymes found in bone and connective tissue which oxidize terminal amino groups of lysine residues in tropocollagen molecules to aldehyde residues. lysyl oxidase
ly·syl ox·i·dase [MIM*153455] an enzyme, which requires Cu2+ and O2, that oxidizes certain lysyl residues in collagen to allysyl residues and hydroxylysyl residues to hydroxyallysyl residues; this is a required step for the cross-linking (via aldol condensations and through Amadori rearrangements) of collagen strands; a lower activity of this enzyme is associated with occipital horn syndrome.Lysyl oxidaseAn enzyme required for the crosslinking of elastin and collagen molecules to form properly functioning connective tissue; present in relatively low levels in at least some forms of cutis laxa.Mentioned in: Cutis LaxaAcronymsSeelog out |