| 释义 |
osteoclastenUK
os·te·o·clast O0142100 (ŏs′tē-ə-klăst′)n.1. A large multinucleate cell found in growing bone that resorbs bony tissue, as in the formation of canals and cavities.2. An instrument used in surgical osteoclasis.
[osteo- + Medieval Latin -clastēs, breaker (from Late Greek -klastēs, from Greek klastos, broken, from klān, to break).]
os′te·o·clas′tic adj.osteoclast (ˈɒstɪəʊˌklæst) n1. (Surgery) a surgical instrument for fracturing bone2. (Physiology) a large multinuclear cell formed in bone marrow that is associated with the normal absorption of bone ˌosteoˈclastic adjos•te•o•clast (ˈɒs ti əˌklæst)
n. 1. a skeletal cell that functions in bone formation. 2. a surgical instrument for effecting osteoclasis. [1870–75; osteo- + -clast < Greek klastós broken] os`te•o•clas′tic, adj. Thesaurus| Noun | 1. | osteoclast - cell that functions in the breakdown and resorption of bone tissuebone cell - a cell that is part of a bone |
TranslationsOsteoclastenUK
osteoclast[′äs·tē·ə‚klast] (histology) A large multinuclear cell associated with bone resorption. (medicine) A large surgical apparatus through which leverage can be exerted to effect osteoclasis. Osteoclast a cell that is involved in the destruction and resorption of bone tissue in vertebrate animals and man. An osteoclast contains from three to several dozen nuclei and a great many lysosomes, whose hydrolytic enzymes upon release from the osteoclasts resorb the mineral matrix of bone and calcified cartilage. osteoclastenUK
osteoclast [os´te-o-klast″] 1. a large, multinuclear cell frequently associated with resorption of bone.2. a surgical instrument used for osteoclasis. adj., adj osteoclas´tic.os·te·o·clast (os'tē-ō-klast'), 1. A large multinucleated cell, possibly of monocytic origin, with abundant acidophilic cytoplasm, functioning in the absorption and removal of osseous tissue. Synonym(s): osteophage2. An instrument used to fracture a bone to correct a deformity. [osteo- + G. klastos, broken] osteoclast (ŏs′tē-ə-klăst′)n.1. A large multinucleate cell found in growing bone that resorbs bony tissue, as in the formation of canals and cavities.2. An instrument used in surgical osteoclasis.
os′te·o·clas′tic adj.osteoclast A cell responsible for reabsorption of bone matrix, which has a central role in bone remodeling.
Morphology
Very large (±100 µm in diameter). It has multiple, relatively uniform, but widely separated round or ovoid nuclei with one or more nucleoli, dense chromatin, abundant blue or purple to pale-pink cytoplasm with many fine red-purple granules.
Origin
Osteoclasts derive from monocyte/macrophage precursors and are unrelated to osteoblasts. Their physiologyic role of bone resorption is linked to charge-coupled proton pumps that secrete acid into the extracellular space.os·te·o·clast (os'tē-ō-klast) 1. A large multinucleated cell, possibly of monocytic origin, with abundant acidophilic cytoplasm, functioning in the absorption and removal of osseous tissue.
Synonym(s): osteophage. 2. An instrument used to fracture a bone to correct a deformity. [osteo- + G. klastos, broken]osteoclast 1. A giant cell containing many nuclei and capable of bone destruction and absorption. Osteoclasts work in conjunction with OSTEOBLASTS in the process of normal bone growth and in bone repair after fractures. 2. A surgical instrument used to fracture bone. osteoclast - a multinucleate ameoboid cell that breaks down bone during growth and remodelling.
- (also called Chomdrioclast) same kind that breaks down cartilage in the transformation to bone.
OsteoclastCell that absorbs bone.Mentioned in: Multiple Myelomaos·te·o·clast (os'tē-ō-klast) 1. Large multinucleated cell, with abundant acidophilic cytoplasm, functioning in absorption and removal of osseous tissue. 2. An instrument used to fracture bone to correct a deformity. osteoclastenUK
Related to osteoclast: calcitonin, osteoclast activating factorWords related to osteoclastnoun cell that functions in the breakdown and resorption of bone tissueRelated Words |