| 释义 |
neuritic plaque
neuritic plaque[nu̇‚rid·ik ′plak] (pathology) Abnormal clumps of degenerating neurons surrounding a core of amyloid protein; a characteristic pathological feature found in the brains of Alzheimer's disease patients. neuritic plaque
neu·rit·ic plaquea spheric mass primarily composed of amyloid fibrils and interwoven neuronal processes, frequently, although not exclusively, observed in Alzheimer disease.senile plaque A histologic finding consisting of a core of extracellular amyloid with an amyloidogenic fragment (betaA4) derived from amyloid precursor protein, surrounded by a tangled spherical mass of argyrophilic cholinergic neuritis (axons/dendrites) seen in the grey matter (neocortex, hippocampus, amygdala, less commonly, basal ganglia and elsewhere) in the brains of older persons, but markedly increased in Alzheimer’s disease.se·nile plaque (sen'il plak) A spheric mass composed primarily of amyloid fibrils and interwoven neuronal processes, frequently, although not exclusively, observed in Alzheimer disease.
Synonym(s): neuritic plaque. |