acetyl:CoA ligase

a·ce·tyl:CoA li·gase

a ligase that catalyzes the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA, a key step in the activation of acetate. Synonym(s): acetate thiokinase, acetate:CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase