acetyl-CoA carboxylase


a·ce·tyl-CoA car·box·yl·ase

a ligase that catalyzes the reaction of acetyl-CoA, CO2, H2O, and ATP, with covalently bound biotin to form malonyl-CoA, ADP, and Pi (or the reverse decarboxylase); N-carboxybiotin is an intermediate. A crucial enzyme in fatty acid synthesis.