acetylcholinesterase inhibitors

acetylcholinesterase inhibitors

Drugs that block the action of the enzyme ACETYLCHOLINESTERASE which quickly breaks down the neurotransmitter acetylcholine. This neurotransmitter is the linking agent between nerve cells in the outer layer (cortex) of the brain. The early impairment of cognitive function found in a common forms of dementia known as dementia with Lewy bodies (DLB) is associated with a reduction in acetylcholine levels. These drugs, by inhibiting, acetylcholine breakdown, have been found helpful in reducing the severity of the early stages of dementia. They cannot be expected to cure or even delay progress of the dementia. The drug group includes DONEPEZIL, GALANTAMINE and RIVASTIGMINE.