merosin


merosin

The muscle isoform of laminin, which is characterised by high-affinity, Ca2+-dependent binding to alpha-dystroglycan, thereby linking the sarcolemmal membrane to the extracellular matrix.

merosin

A glycoprotein normally found in the basement membrane of muscles; it helps muscle cells adhere to and interact with each other and the extracellular matrix. Deficiencies of merosin produce several rare autosomal recessive forms of muscular dystrophy.