| 释义 |
limb-girdle muscular dystrophy
Thesaurus| Noun | 1. | limb-girdle muscular dystrophy - an autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle age; characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle; usually progresses slowly with cardiopulmonary complications in the later stagesdystrophy, muscular dystrophy - any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal musclesautosomal recessive defect, autosomal recessive disease - a disease caused by the presence of two recessive mutant genes on an autosome |
limb-girdle muscular dystrophy
limb-·gir·dle mus·cu·lar dys·tro·phy [MIM*253600] a group of muscular dystrophies, probably heterogeneous in nature. Onset usually in childhood or early adulthood and both sexes affected. Characterized by weakness and wasting, usually symmetric, of the pelvic girdle muscles, the shoulder girdle muscles, or both, but not the facial muscles. Muscle pseudohypertrophy, heart involvement, and mental retardation are absent. Autosomal dominant and recessive inheritance have been described. Synonym(s): Leyden-Möbius muscular dystrophy, pelvofemoral muscular dystrophy, scapulohumeral muscular dystrophylimb-girdle muscular dystrophyn. Any of several forms of muscular dystrophy that chiefly affect the skeletal muscles of the shoulder and pelvic girdles, with symptoms beginning at any age.limb-gir·dle mus·cu·lar dys·tro·phy (lim'gĭr'dĕl mŭs'kyū-lăr dis'trŏ-fē) One of the less well-defined types of this disorder, it is characterized by weakness and wasting, usually symmetric, of the pelvic girdle muscles, the shoulder girdle muscles, or both, but not the facial muscles. Muscle pseudohypertrophy, heart involvement, and mental retardation are absent. Variable inheritance. Limb-girdle muscular dystrophy (LGMD)An autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle age and is characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle; the disease usually progresses slowly with cardio-pulmonary complications in the later stagesMentioned in: Muscular Dystrophy, MyositisLeyden, Ernst V. von, German physician, 1832-1910. Charcot-Leyden crystals - see under CharcotLeyden ataxia - Synonym(s): Westphal-Leyden syndromeLeyden crystals - Synonym(s): Charcot-Leyden crystalsLeyden diseaseLeyden-Möbius muscular dystrophy - Synonym(s): limb-girdle muscular dystrophyLeyden neuritis - fatty degeneration of the fibers of the affected nerve.Westphal-Leyden syndrome - see under Westphal
Möbius, Paul J., German physician, 1853-1907. Leyden-Möbius muscular dystrophy - Synonym(s): limb-girdle muscular dystrophyMöbius sign - impairment of ocular convergence in Graves disease.Möbius I syndrome - moderate migraine accompanied by extraocular palsy. Synonym(s): occasional oculomotor paralysis; ophthalmoplegic migraineMöbius II syndrome - a developmental bilateral facial paralysis usualy associated with oculomotor or other neurological disorders.Synonym(s): congenital facial diplegia; developmental bilateral facial paralysisSee LGMD
See LGMDlimb-girdle muscular dystrophy
Words related to limb-girdle muscular dystrophynoun an autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle ageRelated Words- dystrophy
- muscular dystrophy
- autosomal recessive defect
- autosomal recessive disease
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