| 释义 |
Laband syndrome La·band syn·drome (lah-band'), [MIM*135500 and 135300] fibromatosis of the gingivae associated with hypoplasia of the distal phalanges, nail dysplasia, joint hypermotility, and sometimes hepatosplenomegaly; autosomal dominant inheritance.Zimmermann-Laband syndrome An extremely rare autosomal dominant (OMIM:135500) condition characterised by gingival fibromatosis, hypoplasia of distal phalanges, nail dysplasia, joint hypermobility, hepatosplenomegaly and mental retardation.
Molecular pathology
The defective gene involved in Zimmerman-Laband syndrome has been tentatively localised to chromosome 3p14.3 or 3p21.2.Laband syndrome An AD condition characterized by gingival fibromatosis, whittling of terminal phalanges, floppy ears, defective or absent fingernails, joint hypermobility, ± profound mental retardationLa·band syn·drome (lă-band' sin'drōm) Fibromatosis of the gingivae associated with hypoplasia of the distal phalanges, nail dysplasia, joint hypermotility, and sometimes hepatosplenomegaly; autosomal dominant inheritance. Laband, Peter F., U.S. dentist, 1900–. Laband syndrome - fibromatosis of the gingivae associated with hypoplasia of the distal phalanges, nail dysplasia, joint hypermotility, and sometimes hepatosplenomegaly.La·band syn·drome (lă-band' sin'drōm) [MIM*135500 and 135300] Fibromatosis of gingivae associated with hypoplasia of distal phalanges and nail dysplasia. |