| 释义 |
Li-Fraumeni cancer syndrome Li-Frau·men·i can·cer syn·drome (lē frah'men-ē), [MIM*151623 and 191170] familial breast cancer in young women, with soft-tissue sarcomas in children, brain tumors and other cancers in close relatives; autosomal dominant inheritance, caused by mutation in the P53 gene on chromosome 17p.Fraumeni, Joseph F., Jr., 20th century epidemiologist. Li-Fraumeni cancer syndrome - see under Li
Li, Frederick Pei, epidemiologist, 1940–. Li-Fraumeni cancer syndrome - familial breast cancer in young women, with soft tissue sarcomas in children and other cancers in close relatives. |