| 释义 |
kuru
ku·ru K0116800 (ko͝or′o͞o)n. A fatal degenerative disease of the brain caused by a prion, formerly found among certain peoples of New Guinea and transmitted by the consumption of human flesh during mortuary rites.
[Fore (language of eastern Papua New Guinea).]kuru (ˈkʊruː) n (Pathology) a degenerative disease of the nervous system, restricted to certain tribes in New Guinea, marked by loss of muscular control and thought to be caused by a slow virus[C20: from a native name]ku•ru (ˈkʊər u)
n. a fatal disease of the nervous system, resembling scrapie in sheep, reported among highland New Guinea peoples who ritually eat the brains of their dead kin. [1955–60; < Fore, a language of the Eastern Highlands province of Papua New GuineaPapuan] Thesaurus| Noun | 1. | kuru - a progressive disease of the central nervous system marked by increasing lack of coordination and advancing to paralysis and death within a year of the appearance of symptoms; thought to have been transmitted by cannibalistic consumption of diseased brain tissue since the disease virtually disappeared when cannibalism was abandonednervous disorder, neurological disease, neurological disorder - a disorder of the nervous system |
EncyclopediaSeeprionkuru
prion [pri´on] any of several pathogenic, transmissible forms of the core of prion protein that cause a group of degenerative diseases of the nervous system known as prion diseases. Prions have a structure different from that of normal prion protein, lack detectable nucleic acid, and do not elicit an immune response.prion disease any of a group of fatal degenerative diseases of the nervous system caused by abnormalities in the metabolism of prion protein. These diseases are unique in that they may be transmitted genetically as an autosomal dominant trait, or by infection with abnormal forms of the protein (prions). Inherited forms result from mutations in the gene that codes for prion protein; such mutations may also occur sporadically. Hereditary forms include some forms of Creutzfeldt-Jakob disease, Gerstmann-Sträussler syndrome, and fatal familial insomnia. Infectious forms of the disease result from ingestion of infected tissue or the introduction of infected tissue into the body (kuru" >kuru and some forms of Creutzfeldt-Jakob disease). The latter has occasionally occurred during surgical procedures; it has also occurred as the result of injection of human growth hormone prepared from infected pituitary glands. Prion diseases also occur in animals. Called also transmissible neurodegenerative disease and subacute spongiform or transmissible spongiform encephalopathy.ku·ru (kū'rū), [MIM*245300] A progressive fatal spongiform encephalopathy characterized by ataxia, tremors, lack of coordination, and death. Pathologic lesions in the brain include neuronal loss, astrocytosis, and status spongiosus. Found only in the Fore people in the highlands of New Guinea and transmitted through ritual cannibalism. It was initially attributed to a "slow virus" now known to be caused by prions. See: prion. [native dialect, to shiver from fear or cold] kuru (ko͝or′o͞o)n. A fatal degenerative disease of the brain caused by a prion, formerly found among certain peoples of New Guinea and transmitted by the consumption of human flesh during mortuary rites.A subacute spongiform encephalopathy, caused by a prion which, in its heyday, killed 90% of women in the once cannibalistic Fore tribe of New Guinea—women were most affected as they prepared and ate infected brainsku·ru (kū'rū) A progressive, fatal form of spongiform encephalopathy, endemic in New Guinea and caused by prions. Transmission is believed to occur through ritual cannibalism.
See: prion[native dialect, to shiver from fear or cold]kuru A slow, fatal spongiform encephalopathy that appeared to be limited to natives of the highlands of Papua New Guinea among whom it was spread by the practice of eating the brains of dead relatives. The disease is caused by a PRION, apparently, transmitted through skin abrasions during the preparation of the meal. This explained why kuru affected the women only. The prion is resistant to most of the normal methods of sterilization. The condition features headache, aching joints and limbs, progressive inability to walk and, later, even to sit up, inability to speak and to swallow, sometimes DEMENTIA and eventual death. Research on the Fore tribe in Papua, published in 2006, suggests that the incubation period of vCJD, while averaging 12 years, could be as long as 50 years. See also CREUTZFELDT-JAKOB DISEASE and BOVINE SPONGIFORM ENCEPHALOPATHY.Kuru, New Guinean word meaning "trembling with fear." Kuru disease - fatal neurologic disease which existed in Fore tribe in New Guinea, perpetuated by cannibalism until the practice was abolished.kuru
Related to kuru: Fatal familial insomnia, Gerstmann-Straussler-Scheinker syndromeWords related to kurunoun a progressive disease of the central nervous system marked by increasing lack of coordination and advancing to paralysis and death within a year of the appearance of symptomsRelated Words- nervous disorder
- neurological disease
- neurological disorder
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