| 单词 | aromatase inhibitors |
| 释义 | aromatase inhibitorsar·o·mat·ase in·hib·i·torsaromatase inhibitorsA group of anti-cancer drugs that act by preventing the enzymatic conversion of androgens to oestrogens. These drugs are used especially in post-menopausal women with breast cancers that are being encouraged by oestrogens but that fail to respond to drugs such as tamoxifen. The third-generation aromatase inhibitors, developed in the early 1990s, which include anastrozole (Arimidex), letrozole (Femara) and exemestane (Aromasin), are now challenging tamoxifen as the treatment of choice in post-menopausal women with oestrogen-receptor-positive breast cancers. |
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