| 单词 |
aromatase |
| 释义 |
aromatase
a·ro·ma·tase A5454800 (ə-rō′mə-tāz′, -tāz′)n. A key enzyme in the biosynthesis of steroids, especially in the conversion of androgens to estrogens. [aromat(ic) (because the enzyme increases the number of aromatic carbon rings in the molecular structure of the compounds upon which it acts) + -ase.]aromatase (əˈrəʊməˌteɪz) nan enzyme that converts testosterone into an oestrogenaromatase
aromatase [ah-ro´mah-tās] an enzyme activity occurring in the endoplasmic reticulum and catalyzing the conversion of testosterone to the aromatic compound estradiol.aromatase (ə-rō′mə-tāz′, -tāz′)n. A key enzyme in the biosynthesis of steroids, especially in the conversion of androgens to estrogens.CYP19A1 A gene on chromosome 15q21.1 that encodes a member of the cytochrome P450 superfamily of enzymes, which catalyse reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP19A1 localises to the endoplasmic reticulum and catalyses the last steps of oestrogen biosynthesis—three successive hydroxylations of the A ring of androgens. Molecular pathology CYP19A1 mutations can up- or downregulate aromatase activity.See ARO See ARO |
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