autoantibody

au·to·an·ti·bod·y

A0533100 (ô′tō-ăn′tĭ-bŏd′ē)n. An antibody that reacts with the cells, tissues, or native proteins of the individual in which it is produced.

autoantibody

(ˌɔːtəʊˈæntɪˌbɒdɪ) n, pl -bodies (Biochemistry) an antibody reacting with an antigen that is a part of the organism in which the antibody is formed

au•to•an•ti•bod•y

(ˌɔ toʊˈæn tɪˌbɒd i, -ˈæn ti-)

n., pl. -bod•ies. an antibody that an organism produces against any of its own components. [1905–10]

Thesaurus

Noun

autoantibody - an antibody acting against tissues of the organism that produces itrheumatoid factor - autoantibody that is usually present in the serum of people with rheumatoid arthritisantibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response

autoantibody

[aw″to-an´tĭ-bod″e] an antibody formed in response to, and reacting against, an antigenic constituent of the individual's own tissues.

au·to·an·ti·bod·y

(aw'tō-an'ti-bod-ē), An antibody that occurs in response to antigenic constituents of the host's tissue (or "self antigen") and reacts with the inciting target tissue.

autoantibody

(ô′tō-ăn′tĭ-bŏd′ē)n. An antibody that reacts with the cells, tissues, or native proteins of the individual in which it is produced.

autoantibody

Any antibody produced by an organism against one of its own—self-antigens.
Autoantibodies
Examples of autoantibodies and disease associations
• Anti-actin antibodies—coeliac disease.
• Anti-centromere antibodies—CREST syndrome.
• Anti-ganglioside antibodies—acute motor neuronal neuropathy.
• Antimitochondrial antibody—primary biliary cirrhosis.
• Anti-neutrophil cytoplasmic antibody—Wegener’s granulomatosis (in neutrophil cytoplasm).
• Anti-neutrophil cytoplasmic antibody—Churg-Strauss syndrome, microscopic polyangiitis, systemic vasculitides (perinuclear location).
• Anti-nuclear antibodies (e.g., anti-SSA/Ro)—systemic lupus erythematosus.
• Anti-signal recognition peptide—polymyositis.
• Anti-smooth muscle antibody—chronic autoimmune hepatitis.
• Anti-glomerular basement membrane antibodies.
• Anti-parietal cell antibodies, and others.
• Anti-nuclear antibodies (ANA).
• Anti-smooth muscle actin (SMA).
• Anti-liver-kidney-microsomal antibody (LKM), 2 types:
- Anti-mitochondrial (AMA);
- Perinuclear antineutrophil cytoplasmic (pANCA).
• Anti-soluble liver antigen (SLA), other autoantibodies.
• ANA and SMAs are known to be positive in AIH, PBC, PSC, HCV, HBV, HDV, NASH, drug-induced hepatitis.

autoantibody

Immunology Any antibody produced by an organism against one of its own–self antigens. See Antibody, Hashimoto's thyroiditis, Lupus erythematosus, Myasthenia gravis, Rheumatoid arthritis.

au·to·an·ti·body

(aw'tō-an'ti-bod-ē) Antibody occurring in response to antigenic constituents of the host's tissue, and which reacts with the inciting tissue component.

autoantibody

An antibody derived from the immune system, which then acts against body tissues or constituents.

Autoantibody

An antibody produced by the body in reaction to any of its own cells or cell products.Mentioned in: Antimyocardial Antibody Test, Antinuclear Antibody Test, Autoimmune Disorders, Cold Agglutinins Test, Myasthenia Gravis

au·to·an·ti·body

(aw'tō-an'ti-bod-ē) Antibody occurring in response to antigenic constituents of the host's tissue, and which reacts with the inciting tissue component.

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Words related to autoantibody

noun an antibody acting against tissues of the organism that produces it

Related Words