| Acronym | Definition |
|---|
| LSPE➣Large Scale Polarization Explorer (cosmology) |
| LSPE➣Lunar Seismic Profiling Experiment |
| LSPE➣Least Squares Policy Evaluation (algorithm) |
| LSPE➣Lateral Solid Phase Epitaxy (spectrometry) |
| LSPE➣Licensed Senior Psychological Examiner (various universities) |
| LSPE➣Local Security Policy Editor (Microsoft software component) |
| LSPE➣Lead Specialty Engineer |