multiple malformation syndrome

multiple malformation syndrome

A general term for any of a group of disorders defined by developmental anomalies of two or more organ systems, typically linked to chromosomal damage, teratogens and environmental influences­. Examples include Cornelia de Lange syndrome, Prader-Willi syndrome, Rubinstein-Taybi syndrome and Williams’ syndrome.

multiple malformation syndrome

Any of the developmental anomalies affecting two or more systems in the fetus. The anomalies may be caused by chromosomal and genetic abnormalities or by teratogens, including certain drugs and chemicals. In determining causes, it is important to obtain a complete family history and the history of exposure to known teratogens and infectious diseases. See: amniotic band disruption sequence syndrome