释义 |
Koshland-Nemethy-Filmer model Kosh·land-Né·meth·y-Fil·mer mod·el (KNF mod·el), (kosh'lănd nem'ĕ-thē fil'mĕr), an explanation of the allosteric form of cooperativity. In this model, in the absence of ligands, the oligomeric protein exists in only one conformation; on binding, the ligand induces a conformational change that may be transmitted to other subunits. Synonym(s): Adair-Koshland-Némethy-Filmer model, induced fit model (2) [Daniel E. Koshland, George Némethy, David L. Filmer] Filmer, David L., U.S. biochemist, 1932–. Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer modelKoshland-Némethy-Filmer model - see under Koshland
Koshland, Daniel E., U.S. biochemist, 1920–. Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer modelKoshland-Némethy-Filmer model - a model to explain the allosteric form of cooperativity. Synonym(s): Adair-Koshland-Némethy-Filmer model; induced fit model
Némethy, George, Hungarian-U.S. biochemist, 1934–. Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer modelKoshland-Némethy-Filmer model - see under Koshland |