marginal keratitis
mar·gi·nal ker·a·ti·tis
marginal keratitis
An eye disease characterised by a toxic or hypersensitivity response to bacterial (Staphylococcal) exotoxins.Predisposing factors
Bacterial/staphylococcal blepharitis, recurrent upper respiratory tract infection.
Clinical findings
Ocular pain, lacrimation, red eye, photophobia; ulcer (stromal infiltrate with overlying epithelial loss) that may be round or arcuate, single or multiple, unilateral or bilateral, adjacent to limbus, and separated from limbus by interval of clear cornea; ulcer stains with fluorescein; hyperaemia and oedema of adjacent bulbar conjunctiva.
DiffDx
Contact-lens-associated microbial keratitis, contact-lens-associated corneal infiltrate, rosacea keratitis, Mooren’s ulcer, peripheral keratitis associated with rheumatoid arthritis or other systemic collagen vascular disease, corneal phlyctenulosis, Terrien’s marginal degeneration.