biotin deficiency


biotin deficiency

A rare constellation of clinical findings due to a lack of biotin, which is characterised by anaemia, dry skin, enteritis and hypercholesterolemia. Biotin deficiency is rare, as biotin is formed by intestinal flora; it occurs in those who consume raw eggs. It is a coenzyme in carboxylation reactions.
 
Sources
Egg yolks, milk, tomatoes, yeast.
 
Pathogenesis
Excess consumption of raw egg whites, which are rich in avidin, an egg-white protein that chelates biotin.

biotin deficiency

Clinical nutrition A condition caused by a lack of biotin characterized by anemia, dry skin, enteritis, and hypercholesterolemia; BD is rare, as biotin is formed by intestinal flora; it occurs in those who consume raw eggs.