melanonychia striata

melanonychia striata

A descriptive term for the presence of a longitudinal dark stripe arising in the lunula of a (finger- or toe-) nail bed, and extending to the distal end of the nail in the axis of normal nail growth.
Single melanonychia striata
▪ Neoplastic
– Melanocytic;
– Melanoma;
– Melanocytic hyperplasia;
– Nevus.
▪ Nonmelanocytic
– Bowen's disease;
– Myxoid cyst;
– Wart.
Pseudo-Melanonychia Striata
▪ Haemorrhage
▪ Foreign body
▪ Onychomycosis
Multiple melanonychia striata
▪ Drugs and chemical:
– Antibiotics: cyclines, sulfonamide;
– Antimalarials;
– Beta blockers;
– Chemotherapy;
– Heavy metals: arsenic, gold, mercury;
– Ketoconazole;
– Phenothiazine;
– Psoralen;
– Zidovudine;
▪ Endocrine:
– Corticotropin therapy;
– Corticotropin-producing tumours;
– Melanocyte-stimulating hormone;
– Addison's disease;
– Hyperthyroidism;
– Pregnancy.
▪ Genetic and Ethnic:
– Dark-pigmented persons;
– Peutz-Jeghers syndrome.
▪ Infection and Inflammation:
– Onychomycosis;
– Lichen planus;
– Lichen striatus.
▪ Metabolic and Nutritional:
– Haemochromatosis;
– Haemosiderosis;
– Kwashiorkor;
– Vitamin B12 deficiency.
▪ Miscellaneous:
– Laugier-Hunziker syndrome;
– Carpal tunnel syndrome;
– Radiation;
– Trauma;
– Self-inflicted, onychomania.