释义 |
Marchiafava-Bignami syndrome Marchiafava-Bignami disease A condition that occurs in chronic alcoholics, clinically characterised by progressive neurological disease and histologically characterised by corpus callosum demyelination, necrosis and atrophy.Marchiafava-Bignami syndrome (măr″kē-ă-fă′vă-bē-nyă′mē) [E. Marchiafava, It. pathologist, 1847–1935; A. Bignami, It. physician, 1862–1929] Damage to the white matter of the brain, with dementia, resulting from chronic alcoholism, esp. excessive wine consumption. |