Marchiafava-Bignami disease


Mar·chi·a·fa·va-Big·na·mi dis·ease

(mahr-kē-ă-fah'vah bēn-yah'mē), a disorder recognized primarily by its pathologic features, consisting of demyelination of the corpus callosum and cortical laminar necrosis involving the frontal and temporal lobes. Occurs predominantly in those with chronic alcoholism, particularly wine drinkers.

Marchiafava-Bignami disease

A condition that occurs in chronic alcoholics, clinically characterised by progressive neurological disease and histologically characterised by corpus callosum demyelination, necrosis and atrophy.

Mar·chi·a·fa·va-Big·na·mi dis·ease

(mahr-kē-ă-făh'vah-bēn'yah'mē di-zēz') A disorder characterized by demyelination of the corpus callosum and cortical laminar necrosis involving the frontal and temporal lobes. Occurs predominantly in chronic alcoholics, particularly wine drinkers.

Bignami,

Amico, Italian physician, 1862-1929. Marchiafava-Bignami disease - see under Marchiafava

Marchiafava,

Ettore, Italian pathologist, 1847-1935. Marchiafava syndrome - Synonym(s): Marchiafava-Bignami syndromeMarchiafava-Bignami disease - a disorder consisting of demyelination of the corpus callosum and cortical laminar necrosis involving the frontal and temporal lobes. Synonym(s): Marchiafava syndromeMarchiafava-Micheli anemia - Synonym(s): Marchiafava-Micheli syndromeMarchiafava-Micheli syndrome - an infrequent disorder with insidious onset and chronic course, characterized by episodes of hemolytic anemia, hemoglobinuria, pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly. Synonym(s): Marchiafava-Micheli anemia; paroxysmal nocturnal hemoglobinuria

Mar·chi·a·fa·va-Big·na·mi dis·ease

(mahr-kē-ă-fah'vah-bēn-yah'mē di-zēz') Disorder recognized primarily by its pathologic features, consisting of demyelination of corpus callosum and cortical laminar necrosis involving frontal and temporal lobes.