megaloblastic anaemia

n (Pathology) any anaemia, esp pernicious anaemia, characterized by the presence of megaloblasts in the blood or bone marrow

Thesaurus

Noun

megaloblastic anaemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemiamegaloblastic anemiamalignant anaemia, malignant anemia, pernicious anaemia, pernicious anemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)

megaloblastic anaemia

A type of anaemia characterised by enlarged red cells and a relative reduction in leukocytes and platelets.

Aetiology
Megaloblastic anaemia is typically caused by a deficiency of folic acid and/or vitamin B12, or due to leukaemia, myelofibrosis, myeloma, hereditary disorders, drugs affecting nucleic acid metabolism (e.g., chemotherapeutics, such as methotrexate therapy).

megaloblastic anaemia

Anaemia that features large numbers of abnormally large, nucleated red blood cell precursor cells in the bone marrow and in the blood. This occurs in PERNICIOUS ANAEMIA and in other similar types of anaemia.

megaloblastic anaemia

Related to megaloblastic anaemia: pernicious anaemia, macrocytic anaemia, hypochromic anaemia, sideroblastic anaemia

noun

Synonyms for megaloblastic anaemia

noun anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow

Synonyms

megaloblastic anemia

Related Words

malignant anaemia
malignant anemia
pernicious anaemia
pernicious anemia