nucleosome

nu·cle·o·some

N0187900 (no͞o′klē-ə-sōm′, nyo͞o′-)n. Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones.

nu′cle·o·som′al (-sō′məl) adj.

nucleosome

(ˈnjuːklɪəˌsəʊm) n (Biochemistry) a repeating structural unit of chromatin that contains DNA and histones

nu•cle•o•some

(ˈnu kli əˌsoʊm, ˈnyu-)

n. any of the repeating subunits of chromatin occurring at intervals along a strand of DNA, consisting of DNA coiled around histone. [1960–65]

Translations

nucleosome

enUK

Nucleosome

The fundamental histone-containing structural subunit of eukaryotic chromosomes. In most eukaryotic organisms, nuclear deoxyribonucleic acid (DNA) is complexed with an approximately equal mass of histone protein. The nucleosome is organized so that the DNA is exterior and the histones interior. The DNA makes two turns around a core of eight histone molecules, thus forming a squat cylinder 11 nanometers in diameter and 5.5 nm in height. A short length of linker or spacer DNA connects one nucleosome to the next, forming a nucleosomal chain that has been likened to a beaded string. This basic structure is found in all forms of chromatin. Nucleosomes have been found in all eukaryotic organisms examined, the only exceptions being some sperm nuclei and the dinoflagellate algae.

A chain of adjacent nucleosomes is approximately sixfold shorter than the DNA it contains. Moreover, chains of nucleosomes have the property of self-assembling into thicker fibers in which the DNA packing ratio approaches 35:1. These observations, and the lack of any obvious catalytic activity, have led to the assumption that the primary function of the nucleosome consists of organizing and packing DNA. See Chromosome, Deoxyribonucleic acid (DNA), Gene

nucleosome

[′nü·klē·ə‚sōm] (cell and molecular biology) A morphologically repeating unit of deoxyribonucleic acid (DNA) containing 190 base pairs of DNA folded together with eight histone molecules. Also known as v-body.

nucleosome

[noo´kle-o-sōm″] any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nu·cle·o·some

(nū'klē-ō-sōm'), A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage. Synonym(s): nu body [nucleo- + G. sōma, body]

nucleosome

(no͞o′klē-ə-sōm′, nyo͞o′-)n. Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones.

nu′cle·o·som′al (-sō′məl) adj.

nucleosome

A nucleic acid and protein complex, which is the basic structural unit of chromatin, composed of a segment of DNA wrapped around a core of histone molecules.

nu·cle·o·some

(nū'klē-ō-sōm) A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage. [nucleo- + G. sōma, body]

nucleosome

The structural subunit of CHROMATIN consisting of about 200 BASE PAIRS and a barrel-shaped core of eight histone protein molecules (an octamer).

nucleosome

the basic structural unit of the eukaryote chromosome, being composed of four pairs of HISTONE proteins (H2A, H2B, H3 and H4) that are combined to form an octomer around which is wrapped about 150 nucleotide pairs of DNA.

单词	nucleosome
释义	nucleosome enUK nu·cle·o·some N0187900 (no͞o′klē-ə-sōm′, nyo͞o′-)n. Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones. nu′cle·o·som′al (-sō′məl) adj. nucleosome (ˈnjuːklɪəˌsəʊm) n (Biochemistry) a repeating structural unit of chromatin that contains DNA and histones nu•cle•o•some (ˈnu kli əˌsoʊm, ˈnyu-) n. any of the repeating subunits of chromatin occurring at intervals along a strand of DNA, consisting of DNA coiled around histone. [1960–65] Translations nucleosome enUK Nucleosome The fundamental histone-containing structural subunit of eukaryotic chromosomes. In most eukaryotic organisms, nuclear deoxyribonucleic acid (DNA) is complexed with an approximately equal mass of histone protein. The nucleosome is organized so that the DNA is exterior and the histones interior. The DNA makes two turns around a core of eight histone molecules, thus forming a squat cylinder 11 nanometers in diameter and 5.5 nm in height. A short length of linker or spacer DNA connects one nucleosome to the next, forming a nucleosomal chain that has been likened to a beaded string. This basic structure is found in all forms of chromatin. Nucleosomes have been found in all eukaryotic organisms examined, the only exceptions being some sperm nuclei and the dinoflagellate algae. A chain of adjacent nucleosomes is approximately sixfold shorter than the DNA it contains. Moreover, chains of nucleosomes have the property of self-assembling into thicker fibers in which the DNA packing ratio approaches 35:1. These observations, and the lack of any obvious catalytic activity, have led to the assumption that the primary function of the nucleosome consists of organizing and packing DNA. See Chromosome, Deoxyribonucleic acid (DNA), Gene nucleosome [′nü·klē·ə‚sōm] (cell and molecular biology) A morphologically repeating unit of deoxyribonucleic acid (DNA) containing 190 base pairs of DNA folded together with eight histone molecules. Also known as v-body. nucleosome enUK nucleosome [noo´kle-o-sōm″] any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA. nu·cle·o·some (nū'klē-ō-sōm'), A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage. Synonym(s): nu body [nucleo- + G. sōma, body] nucleosome (no͞o′klē-ə-sōm′, nyo͞o′-)n. Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones. nu′cle·o·som′al (-sō′məl) adj. nucleosome A nucleic acid and protein complex, which is the basic structural unit of chromatin, composed of a segment of DNA wrapped around a core of histone molecules. nu·cle·o·some (nū'klē-ō-sōm) A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage. [nucleo- + G. sōma, body] nucleosome The structural subunit of CHROMATIN consisting of about 200 BASE PAIRS and a barrel-shaped core of eight histone protein molecules (an octamer). nucleosome the basic structural unit of the eukaryote chromosome, being composed of four pairs of HISTONE proteins (H2A, H2B, H3 and H4) that are combined to form an octomer around which is wrapped about 150 nucleotide pairs of DNA.
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