MAP3K6

A gene on chromosome 1p36.11 that encodes a MAPK kinase kinase belonging to a protein kinase signal transduction cascade. MAP3K6 activates the JNK MAPK pathways in response to various signals, including calcium and GPCR signalling and endoplasmic reticulum stress, but does not activate ERK or P38 signalling pathways.

Each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of three protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which in turn activates a specific MAPK.

单词	map3k6
释义	MAP3K6 MAP3K6 A gene on chromosome 1p36.11 that encodes a MAPK kinase kinase belonging to a protein kinase signal transduction cascade. MAP3K6 activates the JNK MAPK pathways in response to various signals, including calcium and GPCR signalling and endoplasmic reticulum stress, but does not activate ERK or P38 signalling pathways. Each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of three protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which in turn activates a specific MAPK.
随便看	path component path computation path computation element path computation policy information model path computation reply path (computing) path connected path-connected component path connectedness path-connectedness path-connected set path connected space path-connected space path-connected topological space path consistency condition path control path control layer path control network path coverage testing path curve path defect indicator path dependent option path-dependent option path-dependent options path descriptor identifier