单词 | lethal midline granuloma |
释义 | lethal midline granulomale·thal mid·line gran·u·lo·malethal midline granulomaThe term is now retired and of historic interest. Lethal midline granuloma was best considered a clinical syndrome rather than a specific histologic lesion, and described as a destructive lesion of the upper respiratory tract—nose, nasopharynx, palate and midface. It was either idiopathic or secondary to lymphoma, malignant histiocytosis or Wegener’s granulomatosis. Many of the lesions formerly designated as lethal midline granoma would now be called angiocentric lymphoma and angiocentric immunoproliferative lesions.lethal midline granulomaA condition confusing to those who read about it and often to those who write about it; LMG is best considered a clinical syndrome rather than a specific histologic lesion; LMG is a destructive lesion of the upper respiratory tract–nose, nasopharynx, palate and midface; it is either idiopathic or 2º to lymphoma, malignant histiocytosis or Wegener's granulomatosis. See Idiopathic midline destructive disease, Malignant histiocytosis, Midline granuloma, Wegener's granulomatosis.le·thal mid·line gran·u·lo·ma(lēthăl midlīn granyū-lōmă)le·thal mid·line gran·u·lo·ma(lēthăl midlīn granyū-lōmă) |
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