| Acronym | Definition |
|---|
| LESI➣Licensing Executives Society International (est. 1965) |
| LESI➣Lake Erie Shores and Islands (Ohio) |
| LESI➣Licenciatura em Engenharia de Sistemas e Informática (Portugese) |
| LESI➣Lake Erie Swimming, Inc. (Ohio) |
| LESI➣Lumbar Epidural Steroid Injection (medical) |