| Acronym | Definition |
|---|
| LESC➣London E-Science Centre |
| LESC➣Law Enforcement Support Center (US Immigration and Customs Enforcement) |
| LESC➣Lower Eastside Service Center |
| LESC➣Loch Earn Sailing Club (UK) |
| LESC➣Lake Elsinore Soaring Club (aviation) |
| LESC➣Lockheed Engineering and Sciences Company |
| LESC➣Lake Eustis Sailing Club (Florida) |
| LESC➣Limbal Epithelial Stem Cell |
| LESC➣Life, Earth and Environmental Standing Committee (European Science Foundation) |
| LESC➣Lifecycle Engineering Solutions Center |
| LESC➣London Electric Supply Corporation, Ltd. |
| LESC➣Lockheed Electronic Systems Company |
| LESC➣Logistics Executive Steering Committee |
| LESC➣Light Engineering Service Center (Pakistan) |