| Acronym | Definition |
|---|
| LES➣Lesbian |
| LES➣Lower East Side (Manhattan) |
| LES➣Large Eddy Simulation |
| LES➣Leave and Earnings Statement |
| LES➣Licensing Executives Society (USA & Canada) |
| LES➣Lower Esophageal Sphincter |
| LES➣London Evening Standard (UK) |
| LES➣Light Emitting Surface (various companies) |
| LES➣Laser Eye Surgery |
| LES➣Lutheran Elementary School (various locations) |
| LES➣Lavell Edwards Stadium (Brigham Young University; Utah) |
| LES➣Launch Entry Suit (US NASA) |
| LES➣Lower Eastern Shore (region) |
| LES➣Lupus Eritematoso Sistemico (Italian) |
| LES➣Law Enforcement Sources |
| LES➣Living Earth Simulator (research project) |
| LES➣Lumines Electronic Symphony (gaming) |
| LES➣Lewis Elementary School (Fort Irwin, CA) |
| LES➣LAN Emulation Server (ATMF) |
| LES➣Lan Emulation Server |
| LES➣Low End System |
| LES➣Linux Enterprise Server |
| LES➣Line Errored Second |
| LES➣Logitech Entertainment System |
| LES➣Load Es Segment |
| LES➣Local Exchange Service (telecommunications) |
| LES➣Legal and Ethical Studies (Arizona State University) |
| LES➣Lake Effect Snow |
| LES➣Line Errored Seconds |
| LES➣Land Earth Station (INMARSAT) |
| LES➣Logistics Execution System |
| LES➣Launch Escape System |
| LES➣Locally Engaged Staff |
| LES➣Law Enforcement Sensitive (security classification) |
| LES➣Linear Expenditure System |
| LES➣Locally Employed Staff |
| LES➣Lambert-Eaton Syndrome |
| LES➣Leading Edge Services |
| LES➣Lazzeri Ermini Salucco (Italian band) |
| LES➣Luxembourg Employment Study |
| LES➣Lincoln Experimental Satellite |
| LES➣Loop Emulation Service |
| LES➣LAN Extension Service |
| LES➣Locally-Enhanced Sampling |
| LES➣Lakeshore Engineering Services (Detroit, MI) |
| LES➣Learning and Evaluation Situation (psychology) |
| LES➣Waste Management Laboratory |
| LES➣Launch Equipment Shop (US NASA) |
| LES➣Low Energy System |
| LES➣Laboratory Equipment Services (various schools) |
| LES➣Laidlaw Environmental Services, Inc |
| LES➣Local Education Service |
| LES➣Local Engineering Specification |
| LES➣Launch Environment Simulator |
| LES➣Life Enhancement Skills (UK FE students) |
| LES➣Laser Evaluator System |
| LES➣Local Excitatory State |
| LES➣Law Enforcement Squadron |
| LES➣Launch Enable System (Titan II) |
| LES➣Launch Effort Simulator |
| LES➣Large Extension Switch |
| LES➣Laboratorio de Energie Solar |
| LES➣Loral Electronics Systems |
| LES➣Lawrence Experimental Station |
| LES➣Launch Enable Switch (US Navy) |
| LES➣Loop Expert Systems (Loop Expert Technologies) |
| LES➣Local Exported Schema |
| LES➣Loaded Equipment Section |
| LES➣Laser and Enterprise Business Solutions (Hewlett-Packard) |
| LES➣Liquid Effluent Services (Office of Scientific and Technical Information; US Department of Energy) |