nephrogenic systemic fibrosis

A rare condition linked to gadolinium-based MRI contrast solutions—in particular Omniscan and OptiMARK, which have a linear non-ionic structure and more likely to release Gd3+ to tissue—characterised by fibrosis of skin, joints, eyes and internal organs, resulting in scleromyxedema/papular mucinosis-like histologic appearance, limitation of joint movement, kidney failure and, in extreme cases, systemic fibrosis affecting the lungs, heart and liver.

Prevention
Some protection may be provided by diethylene-triaminepentaacetic acid.

单词	nephrogenic systemic fibrosis
释义	nephrogenic systemic fibrosis nephrogenic systemic fibrosis A rare condition linked to gadolinium-based MRI contrast solutions—in particular Omniscan and OptiMARK, which have a linear non-ionic structure and more likely to release Gd3+ to tissue—characterised by fibrosis of skin, joints, eyes and internal organs, resulting in scleromyxedema/papular mucinosis-like histologic appearance, limitation of joint movement, kidney failure and, in extreme cases, systemic fibrosis affecting the lungs, heart and liver. Prevention Some protection may be provided by diethylene-triaminepentaacetic acid. AcronymsSeeNSF
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