neonatal hepatitis


ne·o·na·tal hep·a·ti·tis

hepatitis in the neonatal period presumed to be due to any of a variety of causes, chiefly viral; characterized by direct and indirect bilirubinemia, hepatocellular degeneration, and appearance of multinucleated giant cells; may be difficult to distinguish from biliary atresia, but is more likely to end with recovery, although cirrhosis may develop. Synonym(s): giant cell hepatitis

neonatal 'hepatitis'

A generic term for diseases of the newborn hepatic parenchyma, commonly associated with ↑ conjugated hyperbilirubinemia Diagnosis Requires ≥ 3 of following: fatty changes, cholestasis, bile duct proliferation, fibrosis, pseudoacini, cirrhosis Etiology Infection–syphilis, listeriosis, HBV, rubella, CMV, echovirus, adenovirus, toxoplasmosis, metabolic disease–α1-antitrypsin deficiency, cystic fibrosis, Wilson's disease, galactosemia, fructosuria, tyrosinemia, mechanical–choledochal cysts, intrahepatic ductal atresia hypoplasia, familial intrahepatic cholestasis, HDN, etc. See Hemolytic disease of the newborn. Cf Giant cell hepatitis.

ne·o·na·tal hep·a·ti·tis

(nē'ō-nā'tăl hep'ă-tī'tis) The disorder in the neonatal period attributable to a variety of causes, chiefly viral.

ne·o·na·tal hep·a·ti·tis

(nē'ō-nā'tăl hep'ă-tī'tis) Neonatal disorder due to chiefly viral pathogens.