mucopolysaccharide

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mu·co·pol·y·sac·cha·ride

M0462800 (myo͞o′kō-pŏl′ē-săk′ə-rīd′)n. See glycosaminoglycan.

mucopolysaccharide

(ˌmjuːkəʊˌpɒlɪˈsækəraɪd) n (Biochemistry) biochem any of a group of complex polysaccharides composed of repeating units of two sugars, one of which contains an amino group

gly•cos•a•mi•no•gly•can

(ˌglaɪ koʊs əˌmi noʊˈglaɪ kæn)

n. any of a class of polysaccharides that form mucins when complexed with proteins. Formerly, mucopolysaccharide. [1975–80; glyco- + (hexo)samin(e) a hexose derivative + -o- + glycan polysaccharide]
Thesaurus
Noun1.mucopolysaccharide - complex polysaccharides containing an amino group; occur chiefly as components of connective tissuehyaluronic acid - a viscous mucopolysaccharide found in the connective tissue space and the synovial fluid of movable joints and the humors of the eye; a cementing and protective substancepolyose, polysaccharide - any of a class of carbohydrates whose molecules contain chains of monosaccharide molecules
References in periodicals archiveMucopolysaccharidosis type I (MPS-I) is a rare inherited neurometabolic disease caused by a deficiency of the IDUA (alpha-L-iduronidase) lysosomal enzyme required to break down glycosaminoglycans (also known as GAGs or mucopolysaccharides).Orchard Therapeutics Announces Presentation of Data from Neurometabolic Portfolio at Upcoming Society for the Study of Inborn Errors of Metabolism 2019 Annual SymposiumThe mucous cells of each kind of fish skin were divided into four types by AB-PAS staining: type I mucous cells contained PAS-positive neutral mucopolysaccharides and were stained red; type II mucous cells contained PAS-negative acid mucopolysaccharides and were stained blue; type III mucous cells contained mainly neutral mucopolysaccharides, together with small quantities of acid mucopolysaccharides, the cell were stained purple-reddish; type IV mucous cells contained mainly acid mucopolysaccharides, together with small quantities of neutral mucopolysaccharides, the cell were stained bluish violet.The Structure of the Skin, Types and Distribution of Mucous Cell of Yangtze Sturgeon (Acipenser dabryanus)/La Estructura de la Piel, los Tipos y Distribucion de las Celulas Mucosas del Esturion Yangtze (Acipenser dabryanus)* Collagen Types I,II,V,X and Mucopolysaccharides - advanced collagen recovery compoundCertified Nutraceuticals, IncIn some insects, there is a spermathecal gland containing a secretion rich in glycogen, glycoproteins, phospholipids and mucopolysaccharides (Bhatnagar and Musgrave, 1971; Wolfner, 2011; Pascini and Martins, 2017), which is released in the reservoir lumen to contribute to the maintenance of the spermatozoa viability.Morphology of the spermatheca of Triatoma lecticularia (Hemiptera: Reduviidae) (Stal, 1859)/Morfologia da espermateca de Triatoma lecticularia (Hemiptera: Reduviidae) (Stal, 1859)The stains corresponded to: hematoxylin and eosin, for general histology analysis; Alcian blue, Toluidine blue and Masson's trichrome, to identify ECGs cells and characterize the content of their granules, and performic acid and Schiff reagent (PAS), to detect mucopolysaccharides.Histopathological changes induced by Caligus rogercresseyi in rainbow trout (Oncorhynchus mykiss)For the chondrogenic cultures, spherical micro-mass cultures were observed, and deposits of acid mucopolysaccharides were confirmed with Alcian blue staining as shown in Fig.Evaluation and Assessment of Differentiation Potential of Human Adipose-derived Stem Cells on Chitosan HydrogelLaboratory investigations following newborn screen, plasma amino acids, urine organic and amino acids, mucopolysaccharides, and oligosaccharides were all normal.Exome Sequencing Identifies a Novel Sorting Nexin 14 Gene Mutation Causing Cerebellar Atrophy and Intellectual DisabilityThe doctors in California administered the experimental intravenous treatment, which provides the body with instructions to change DNA, on Brian Madeux, who suffers from Hunter's syndrome.
People with Hunter's syndrome are unable to break down long, sugary molecules called mucopolysaccharides. This leads to the molecules building up and causing brain and organ damage, and in severe cases it can be fatal.
Sufferers require regular enzyme replacement therapy, but Madeux said he opted to take part in a trial as he was "in pain every second of the day".
The 44-year-old from Arizona underwent the treatment at UCSF Benioff Children's Hospital in Oakland on Monday.Doctors carry out first gene editing inside patientHunter's syndrome is a rare disease in which people are born without the genetic instructions for an enzyme that breaks down long sugary molecules called mucopolysaccharides. As a consequence, mucopolysaccharides accumulate in the body and damage the brain and other organs.Gene-editing completed from within a human body for the first timeMucopolysaccharides, smooth muscle cells and fibroblasts thicken the intima.PERIPARTUM ANAESTHETIC MANAGEMENT OF TWIN GESTATIONAL PREGNANCY IN PATIENT WITH TAKAYASU'S ARTERITISSalivary calculi consist primarily of calcium phosphate, carbonate hydroxyapatite in combination with an organic matrix of glycoproteins, and mucopolysaccharides. Small amounts of other salts such as magnesium, potassium, and ammonium are also involved in calculus formation.Giant Submandibular Calculus Eroding Oral Cavity Mucosa