| 单词 |
lefty2 |
| 释义 |
LEFTY2 LEFTY2 A gene on chromosome 1q42.1 that encodes a member of the transforming growth factor beta (TGFB) family of cytokines that plays a role in determining left-right asymmetry during organogenesis and may also play a role in endometrial bleeding.
Molecular pathology
LEFTY2 mutations are associated with left-right axis malformations, especially in the heart and lungs; some types of infertility are associated with dysregulated LEFTY2 expression in the endometrium. |
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