N-acetylglutamate

N-a·ce·tyl·glu·ta·mate (NAG),

(a-sĕ'til-glū'tă-māt), The salt of N-acetylglutamic acid. An activator of carbamoyl phosphate synthetase I during urea synthesis; this amino acid causes a configurational change in the enzyme, thus increasing its activity. The inability to synthesize N-acetylglutamate results in a defect in urea biosynthesis.