meconium plug syndrome
meconium ileus
A condition characterised by obstruction of the neonatal intestine by meconium that may be confined to the ileus, a finding characteristic of cystic fibrosis.Clinical findings
Non-passage of stool in the first two days of life, vomiting, abdominal distension.
Complications
Volvulus, intestinal infarction.
DiffDx
Meconium “plugging” of the rectum may also signal the presence of Hirschsprung’s disease, which is histologically characterised by segmental aganglionosis.