nelfinavir
enUKnel·fin·a·vir
N0054450 (nĕl-fĭn′ə-vîr)| Noun | 1. | nelfinavir - a protease inhibitor (trade name Viracept) used in treating HIV usually in combination with other drugs |
| 单词 | nelfinavir | |||
| 释义 | nelfinavirenUKnel·fin·a·virN0054450 (nĕl-fĭn′ə-vîr)
nelfinavirenUKnelfinavir[nel-fin´ah-vir]nelfinavir(nĕl-fĭn′ə-vîr)nelfinavirA potent HIV protease inhibitor, which is combined with reverse transcriptase inhibitors—e.g., Retrovir (AZT), zidovudine and Epivir (3TC, lamivudine)—acting at late stages in the HIV life cycle.Side effects Diarrhoea, 20%, increased liver function tests (LFTs), lipodystrophy. Contraindicated drugs Nelfinavir inhibits the cytochrome P-450 system, precluding co-administration of agents (e.g., amiodarone, astemizole, cisapride, ergot derivatives, midazolam, quinidine, rifampin, terfenadine, triazolam) which are metabolised by the P-450 system. nelfinavirViracept® AIDS A potent HIV protease inhibitor, used with reverse transcriptase inhibitors–eg, Retrovir–AZT, zidovudine and Epivir–3TC, lamivudine; it acts at late stages in the viral life cycle Side effects Diarrhea–20%, ↑ LFTs, lipodystrophy. See AIDS, Antiretroviral, HIV, Protease inhibitors. Cf Reverse transcriptase inhibitor.nelfinavirA protease inhibitor drug used in combination with other antiretroviral drugs to treat HIV infections. The drug is on the WHO official list. A brand name is Viracept.nelfinavirenUK
Synonyms for nelfinavir
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