malignant cerebral oedema

An uncommon, often fatal complication of traumatic brain injury, which is more common in children and adolescents. It is diagnosed by a rapid increase in intracranial pressure shortly after injury, is refractory to medical management, and attributed to global cytotoxic oedema due to activation of apoptotic pathways and failure of energy metabolism.
Management
Multi-modality neuromonitoring, osmotic diuretics, CSF drainage via an extraventricular drain, sedation and paralytics, avoid hyponatremia; pCO2 should be maintained at the low end of the normal 35–45 mm Hg range, and intracranial pressure maintained at < 20 mm Hg.

单词	malignant cerebral oedema
释义	malignant cerebral oedema malignant cerebral oedema An uncommon, often fatal complication of traumatic brain injury, which is more common in children and adolescents. It is diagnosed by a rapid increase in intracranial pressure shortly after injury, is refractory to medical management, and attributed to global cytotoxic oedema due to activation of apoptotic pathways and failure of energy metabolism. Management Multi-modality neuromonitoring, osmotic diuretics, CSF drainage via an extraventricular drain, sedation and paralytics, avoid hyponatremia; pCO2 should be maintained at the low end of the normal 35–45 mm Hg range, and intracranial pressure maintained at < 20 mm Hg.
随便看	macie maciej kamienski maciej miechowita maciej nalecz maciej of miechow maciej of miechów macies macif macified mac ii mac iicx macil macilency macilent mac imagery transmission system macimmobility macims macinac bridge mac independent function mac infection macing macinnes, colin macinnes, helen mac intel macintosh