Maldonado-San Jose stain

Mal·do·na·do-San Jo·se stain

(mahl-dō-nah'dō san hō-zā'), a staining method for staining pancreatic islet cells, using a phloxine-azure B-hematoxylin sequence; alpha cells are purple, beta cells are violet-blue, delta cells are light blue, and exocrine cells are grayish blue with red secretion granules.

Maldonado-San Jose stain

A near-extinct histologic method using phloxine, azure B and hematoxylin, in sequence, to differentiate the cell types in the pancreatic islets. It has been largely superseded by specific immunocytochemical methods for the identification of insulin, glucagon, somatostatin and pancreatic polypeptide within islet cells.

Maldonado,

(origin unknown). Maldonado-San Jose stain - method for staining pancreatic islet cells.

San Jose,

Hermenia, 20th century Chilean pathologist. Maldonado-San Jose stain - see under Maldonado