| Acronym | Definition |
|---|
| MSFC➣Marshall Space Flight Center |
| MSFC➣Multilayer Switch Feature Card (Cisco Systems) |
| MSFC➣Multilayer Switch Feature Card |
| MSFC➣Medical Students For Choice |
| MSFC➣Metropolitan Sports Facilities Commission (Minneapolis, MN) |
| MSFC➣Melbourne Science Fiction Club (Melbourne, Australia) |
| MSFC➣Malia and Sasha Fan Club (Obama children) |
| MSFC➣Million Standard Cubic Feet (gas measurement) |
| MSFC➣Microsoft Foundation Classes |
| MSFC➣Mobile Strike Force Command (US Army Special Forces) |
| MSFC➣Mighty Sad Funpu Chicken (gaming group) |
| MSFC➣Marine Sciences and Fisheries Centre (Oman) |