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loiasis
loiasis[‚lȯi′ā·səs] (medicine) A filariasis of tropical Africa, caused by the filaria Loa, and characterized by diurnal periodicity of microfilariae in the blood, and transient cutaneous swelling caused by migrating adult worms. loiasis
loiasis [lo-i´ah-sis] infection with nematodes of the genus Loa; called also loaiasis.lo·i·a·sis (lō-ī'ă-sis), A chronic disease caused by the filarial nematode Loa loa, with symptoms and signs first occurring approximately 3-4 years after a bite by an infected tabanid fly. When the infective larvae mature, the adult worms move about in an irregular course through the connective tissue of the body (as rapidly as 1 cm/minute), frequently becoming visible beneath the skin and mucous membranes; for example, in the back, scalp, chest, inner surface of the lip, and especially on the conjunctiva. The worms provoke hyperemia and exudation of fluid, often a host response to the worm products, a Calabar or fugitive swelling that causes no serious damage and subsides as the parasites move on; the patient is annoyed by the "creeping" in the tissues and intense itching, as well as occasional pain, especially when the swelling is in the region of tendons and joints. Many patients have marked eosinophilia (10-40%). Synonym(s): Calabar swelling, fugitive swellinglo·i·a·sis (lō-ī'ă-sis) A chronic disease caused by the filarial nematode Loa loa; symptoms first occur 3-4 years after a bite by an infected tabanid fly. When the larvae mature, the adult worms move about through connective tissue, frequently becoming visible beneath the skin and mucous membranes or while passing through the conjunctiva. The worms provoke hyperemia and exudation of fluid; the patient is annoyed by the perception of "creeping" in the tissues and intense itching, as well as occasional pain, especially when the swelling is in the region of tendons and joints. loiasis A type of FILARIASIS caused by the microfilarial worm parasite Loa loa . The disease occurs in Central and West Africa and features prominent lumps under the skin (Calabar swellings) caused by inflammatory reaction to the migrating worms. The adult worm sometimes appears under the CONJUNCTIVA of the eye. Also known as eye worm. |