alendronate

a·len·dro·nate

A0189550 (ə-lĕn′drə-nāt′)n. A bisphosphonate drug, C₄H₁₃NO₇P₂, that inhibits bone resorption and is used in the form of its sodium salt to treat and prevent osteoporosis in postmenopausal women.

[Probably a(mino) + (buty)l(id)en(e), one of its constituents (butyl + -id(e) + -ene) + (hy)dr(oxy) + (bisphosph)onate.]

Thesaurus

Noun

alendronate - a tablet (trade name Fosamax) prescribed to prevent or treat osteoporosis in women after menopauseFosamaxmedicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease

Translations

alendronate

enUK

alendronate

[ah-len´dro-nāt] a calcium-regulating agent used in the form of the sodium salt to inhibit resorption of bone in the treatment of osteitis deformans, osteoporosis, and hypercalcemia related to malignancy; administered orally.

alendronate

(ə-lĕn′drə-nāt′)n. A bisphosphonate drug, C₄H₁₃NO₇P₂, that inhibits bone resorption and is used in the form of its sodium salt to treat and prevent osteoporosis in postmenopausal women.

alendronate

A biphosphonate used to treat postmenopausal osteoporosis and Paget’s disease of bone. Alendronate reduces vertebral fractures by 48% and other fractures by 21%, increases bone density by 9% and density of the hip bones by 6% over 3 years of therapy.
Adverse effects
Nausea, stomach pain, constipation, diarrhoea, bloating, headaches, dizziness, swelling of joints (especially of hands and feet).
Mechanism of action
Marked inhibition of bone resorption by inhibiting osteoclastic activity and number of osteoclasts by reducing recruitment, and increasing apoptosis.

alendronate

Fosamax^® Endocrinology A biphosphonate used to treat postmenopausal osteoporosis and Paget's disease of bone. See Osteoporosis. Cf Salmon calcitonin.

alendronate

A drug used in the prevention and treatment of post-menopausal OSTEOPOROSIS. A brand name is Fosamax.

Alendronate

A nonhormonal drug used to treat osteoporosis in postmenopausal women.Mentioned in: Osteoporosis

alendronate

(ă-lendrŏ-nāt) A bisphosphonate drug used to treat osteoporosis. [coined term based on parts of the chemical name]

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Synonyms for alendronate

noun a tablet (trade name Fosamax) prescribed to prevent or treat osteoporosis in women after menopause

Synonyms

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