单词 | jam3 | |||
释义 | JAM3JAM3A gene on chromosome 11q25 that encodes a member of the immunoglobulin superfamily, which localises in the tight junctions between high endothelial cells of lymph nodes and acts as a counter-receptor for ITGAM, mediating leukocyte-platelet interactions. It is involved in regulating transepithelial migration of polymorphonuclear neutrophils.JAM3
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