ITGB3

A gene on chromosome 17q25 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed one of 18 different alpha and one of 8 different beta chains). The beta-3 chain partners with the alpha-IIb chain and acts as a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, vitronectin and platelets. Beta-3 chain partnered with the alpha-5 chain is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.

单词	itgb3
释义	ITGB3 ITGB3 A gene on chromosome 17q25 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed one of 18 different alpha and one of 8 different beta chains). The beta-3 chain partners with the alpha-IIb chain and acts as a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, vitronectin and platelets. Beta-3 chain partnered with the alpha-5 chain is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
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