ITGA2

A gene on chromosome 5q11.2 that encodes an integrin alpha chain protein which, like all integrins, forms a heterodimer with a beta chain, thereby participating in an array of cell-cell and cell-matrix interactions, playing a major role in cell migration, organ and tissue development and differentiation. Alpha-2 beta-1 heterodimers serve as receptors for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin, and is responsible for adhesion of platelets and other cells to the extracellular matrix, modulation of collagen and collagenase gene expression and organisation of newly synthesised extracellular matrix.

单词	itga2
释义	DictionarySeeBREncyclopediaSeebr ITGA2 ITGA2 A gene on chromosome 5q11.2 that encodes an integrin alpha chain protein which, like all integrins, forms a heterodimer with a beta chain, thereby participating in an array of cell-cell and cell-matrix interactions, playing a major role in cell migration, organ and tissue development and differentiation. Alpha-2 beta-1 heterodimers serve as receptors for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin, and is responsible for adhesion of platelets and other cells to the extracellular matrix, modulation of collagen and collagenase gene expression and organisation of newly synthesised extracellular matrix. ThesaurusSeeBr
随便看	gluco- glucoamylase glucoascorbic acid glucobay glucocerebrosidase glucocerebroside glucochloral glucochloralose gluco corticoid glucocorticoid glucocorticoid accessory factor 1 glucocorticoid attenuated response genes glucocorticoid deficiency 1 glucocorticoid deficiency and achalasia glucocorticoid deficiency type 1 glucocorticoid factor glucocorticoid hypersensitivity glucocorticoid induced leucine zipper glucocorticoid induced osteoporosis glucocorticoid-induced osteoporosis glucocorticoid-induced receptor glucocorticoid-induced tnf (tumor necrosis factor) receptor ligand glucocorticoid-inducible p450 glucocorticoid membrane binding site glucocorticoid modulatory element-binding