| Acronym | Definition |
|---|
| ISSSC➣Institute for the Study of Secularism in Society and Culture (Trinity College) |
| ISSSC➣International Seniors' Speed Skating Committee |
| ISSSC➣International Seppala Siberian Sleddog Club |
| ISSSC➣International Society for the Suppression of Savage Customs (fictional society; Heart of Darkness) |