| Acronym | Definition |
|---|
| ISSO➣Information System Security Officer |
| ISSO➣International Students and Scholars Office (college) |
| ISSO➣Institute for Space Systems Operations |
| ISSO➣Institute for Social and Sustainable Oikonomics (Germany) |
| ISSO➣Information Systems Security Organization |
| ISSO➣Information Systems Student Organization (various schools) |
| ISSO➣International Side Saddle Organization (Stevensville, MD) |
| ISSO➣Information Systems Security Office |
| ISSO➣International Swaminarayan Satsang Organization |
| ISSO➣Information Services Support Office (Army) |
| ISSO➣International Self-Service Organization |