单词 | ing5 |
释义 | ING5ING5A gene on chromosome 2q37.3 that encodes inhibitor of growth (ING) family member 5, a component of the HBO1 complex responsible for the bulk of histone H4 acetylation in vivo. ING5 is also a component of the MOZ/MORF complex, which has histone H3 acetyltransferase activity. It may regulate DNA replication and act as a transcriptional coactivator by acetylating chromatin. |
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